Pesquisa | BVS Violência e Saúde

1.

It took a long, long time: Ras and the race to cure cancer.

Weinberg, Robert A.

Cell ; 187(7): 1574-1577, 2024 Mar 28.

Artigo em Inglês | MEDLINE | ID: mdl-38552606

2.

Chromatin remodeling of histone H3 variants by DDM1 underlies epigenetic inheritance of DNA methylation.

Lee, Seung Cho; Adams, Dexter W; Ipsaro, Jonathan J; Cahn, Jonathan; Lynn, Jason; Kim, Hyun-Soo; Berube, Benjamin; Major, Viktoria; Calarco, Joseph P; LeBlanc, Chantal; Bhattacharjee, Sonali; Ramu, Umamaheswari; Grimanelli, Daniel; Jacob, Yannick; Voigt, Philipp; Joshua-Tor, Leemor; Martienssen, Robert A.

Cell ; 186(19): 4100-4116.e15, 2023 09 14.

Artigo em Inglês | MEDLINE | ID: mdl-37643610

3.

Systemic vaccination induces CD8⁺ T cells and remodels the tumor microenvironment.

Baharom, Faezzah; Ramirez-Valdez, Ramiro A; Khalilnezhad, Ahad; Khalilnezhad, Shabnam; Dillon, Marlon; Hermans, Dalton; Fussell, Sloane; Tobin, Kennedy K S; Dutertre, Charles-Antoine; Lynn, Geoffrey M; Müller, Sören; Ginhoux, Florent; Ishizuka, Andrew S; Seder, Robert A.

Cell ; 185(23): 4317-4332.e15, 2022 11 10.

Artigo em Inglês | MEDLINE | ID: mdl-36302380

4.

Protection from SARS-CoV-2 Delta one year after mRNA-1273 vaccination in rhesus macaques coincides with anamnestic antibody response in the lung.

Gagne, Matthew; Corbett, Kizzmekia S; Flynn, Barbara J; Foulds, Kathryn E; Wagner, Danielle A; Andrew, Shayne F; Todd, John-Paul M; Honeycutt, Christopher Cole; McCormick, Lauren; Nurmukhambetova, Saule T; Davis-Gardner, Meredith E; Pessaint, Laurent; Bock, Kevin W; Nagata, Bianca M; Minai, Mahnaz; Werner, Anne P; Moliva, Juan I; Tucker, Courtney; Lorang, Cynthia G; Zhao, Bingchun; McCarthy, Elizabeth; Cook, Anthony; Dodson, Alan; Teng, I-Ting; Mudvari, Prakriti; Roberts-Torres, Jesmine; Laboune, Farida; Wang, Lingshu; Goode, Adrienne; Kar, Swagata; Boyoglu-Barnum, Seyhan; Yang, Eun Sung; Shi, Wei; Ploquin, Aurélie; Doria-Rose, Nicole; Carfi, Andrea; Mascola, John R; Boritz, Eli A; Edwards, Darin K; Andersen, Hanne; Lewis, Mark G; Suthar, Mehul S; Graham, Barney S; Roederer, Mario; Moore, Ian N; Nason, Martha C; Sullivan, Nancy J; Douek, Daniel C; Seder, Robert A.

Cell ; 185(1): 113-130.e15, 2022 01 06.

Artigo em Inglês | MEDLINE | ID: mdl-34921774

5.

Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.

Williams, Wilton B; Meyerhoff, R Ryan; Edwards, R J; Li, Hui; Manne, Kartik; Nicely, Nathan I; Henderson, Rory; Zhou, Ye; Janowska, Katarzyna; Mansouri, Katayoun; Gobeil, Sophie; Evangelous, Tyler; Hora, Bhavna; Berry, Madison; Abuahmad, A Yousef; Sprenz, Jordan; Deyton, Margaret; Stalls, Victoria; Kopp, Megan; Hsu, Allen L; Borgnia, Mario J; Stewart-Jones, Guillaume B E; Lee, Matthew S; Bronkema, Naomi; Moody, M Anthony; Wiehe, Kevin; Bradley, Todd; Alam, S Munir; Parks, Robert J; Foulger, Andrew; Oguin, Thomas; Sempowski, Gregory D; Bonsignori, Mattia; LaBranche, Celia C; Montefiori, David C; Seaman, Michael; Santra, Sampa; Perfect, John; Francica, Joseph R; Lynn, Geoffrey M; Aussedat, Baptiste; Walkowicz, William E; Laga, Richard; Kelsoe, Garnett; Saunders, Kevin O; Fera, Daniela; Kwong, Peter D; Seder, Robert A; Bartesaghi, Alberto; Shaw, George M.

Cell ; 184(11): 2955-2972.e25, 2021 05 27.

Artigo em Inglês | MEDLINE | ID: mdl-34019795

6.

Single-Cell Transcriptome Atlas of Murine Endothelial Cells.

Kalucka, Joanna; de Rooij, Laura P M H; Goveia, Jermaine; Rohlenova, Katerina; Dumas, Sébastien J; Meta, Elda; Conchinha, Nadine V; Taverna, Federico; Teuwen, Laure-Anne; Veys, Koen; García-Caballero, Melissa; Khan, Shawez; Geldhof, Vincent; Sokol, Liliana; Chen, Rongyuan; Treps, Lucas; Borri, Mila; de Zeeuw, Pauline; Dubois, Charlotte; Karakach, Tobias K; Falkenberg, Kim D; Parys, Magdalena; Yin, Xiangke; Vinckier, Stefan; Du, Yuxiang; Fenton, Robert A; Schoonjans, Luc; Dewerchin, Mieke; Eelen, Guy; Thienpont, Bernard; Lin, Lin; Bolund, Lars; Li, Xuri; Luo, Yonglun; Carmeliet, Peter.

Cell ; 180(4): 764-779.e20, 2020 02 20.

Artigo em Inglês | MEDLINE | ID: mdl-32059779

7.

An immunodominant NP_105-113-B*07:02 cytotoxic T cell response controls viral replication and is associated with less severe COVID-19 disease.

Peng, Yanchun; Felce, Suet Ling; Dong, Danning; Penkava, Frank; Mentzer, Alexander J; Yao, Xuan; Liu, Guihai; Yin, Zixi; Chen, Ji-Li; Lu, Yongxu; Wellington, Dannielle; Wing, Peter A C; Dominey-Foy, Delaney C C; Jin, Chen; Wang, Wenbo; Hamid, Megat Abd; Fernandes, Ricardo A; Wang, Beibei; Fries, Anastasia; Zhuang, Xiaodong; Ashley, Neil; Rostron, Timothy; Waugh, Craig; Sopp, Paul; Hublitz, Philip; Beveridge, Ryan; Tan, Tiong Kit; Dold, Christina; Kwok, Andrew J; Rich-Griffin, Charlotte; Dejnirattisa, Wanwisa; Liu, Chang; Kurupati, Prathiba; Nassiri, Isar; Watson, Robert A; Tong, Orion; Taylor, Chelsea A; Kumar Sharma, Piyush; Sun, Bo; Curion, Fabiola; Revale, Santiago; Garner, Lucy C; Jansen, Kathrin; Ferreira, Ricardo C; Attar, Moustafa; Fry, Jeremy W; Russell, Rebecca A; Stauss, Hans J; James, William; Townsend, Alain.

Nat Immunol ; 23(1): 50-61, 2022 01.

Artigo em Inglês | MEDLINE | ID: mdl-34853448

8.

Dual Sensing of Physiologic pH and Calcium by EFCAB9 Regulates Sperm Motility.

Hwang, Jae Yeon; Mannowetz, Nadja; Zhang, Yongdeng; Everley, Robert A; Gygi, Steven P; Bewersdorf, Joerg; Lishko, Polina V; Chung, Jean-Ju.

Cell ; 177(6): 1480-1494.e19, 2019 05 30.

Artigo em Inglês | MEDLINE | ID: mdl-31056283

9.

Therapeutic Ligands Antagonize Estrogen Receptor Function by Impairing Its Mobility.

Guan, Jane; Zhou, Wei; Hafner, Marc; Blake, Robert A; Chalouni, Cecile; Chen, Irene P; De Bruyn, Tom; Giltnane, Jennifer M; Hartman, Steven J; Heidersbach, Amy; Houtman, Rene; Ingalla, Ellen; Kategaya, Lorn; Kleinheinz, Tracy; Li, Jun; Martin, Scott E; Modrusan, Zora; Nannini, Michelle; Oeh, Jason; Ubhayakar, Savita; Wang, Xiaojing; Wertz, Ingrid E; Young, Amy; Yu, Mamie; Sampath, Deepak; Hager, Jeffrey H; Friedman, Lori S; Daemen, Anneleen; Metcalfe, Ciara.

Cell ; 178(4): 949-963.e18, 2019 08 08.

Artigo em Inglês | MEDLINE | ID: mdl-31353221

10.

An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma.

Maun, Henry R; Jackman, Janet K; Choy, David F; Loyet, Kelly M; Staton, Tracy L; Jia, Guiquan; Dressen, Amy; Hackney, Jason A; Bremer, Meire; Walters, Benjamin T; Vij, Rajesh; Chen, Xiaocheng; Trivedi, Neil N; Morando, Ashley; Lipari, Michael T; Franke, Yvonne; Wu, Xiumin; Zhang, Juan; Liu, John; Wu, Ping; Chang, Diana; Orozco, Luz D; Christensen, Erin; Wong, Manda; Corpuz, Racquel; Hang, Julie Q; Lutman, Jeff; Sukumaran, Siddharth; Wu, Yan; Ubhayakar, Savita; Liang, Xiaorong; Schwartz, Lawrence B; Babina, Magda; Woodruff, Prescott G; Fahy, John V; Ahuja, Rahul; Caughey, George H; Kusi, Aija; Dennis, Mark S; Eigenbrot, Charles; Kirchhofer, Daniel; Austin, Cary D; Wu, Lawren C; Koerber, James T; Lee, Wyne P; Yaspan, Brian L; Alatsis, Kathila R; Arron, Joseph R; Lazarus, Robert A; Yi, Tangsheng.

Cell ; 179(2): 417-431.e19, 2019 Oct 03.

Artigo em Inglês | MEDLINE | ID: mdl-31585081

11.

Robust IgM responses following intravenous vaccination with Bacille Calmette-Guérin associate with prevention of Mycobacterium tuberculosis infection in macaques.

Irvine, Edward B; O'Neil, Anthony; Darrah, Patricia A; Shin, Sally; Choudhary, Alok; Li, Wenjun; Honnen, William; Mehra, Smriti; Kaushal, Deepak; Gideon, Hannah Priyadarshini; Flynn, JoAnne L; Roederer, Mario; Seder, Robert A; Pinter, Abraham; Fortune, Sarah; Alter, Galit.

Nat Immunol ; 22(12): 1515-1523, 2021 12.

Artigo em Inglês | MEDLINE | ID: mdl-34811542

12.

Intravenous nanoparticle vaccination generates stem-like TCF1⁺ neoantigen-specific CD8⁺ T cells.

Baharom, Faezzah; Ramirez-Valdez, Ramiro A; Tobin, Kennedy K S; Yamane, Hidehiro; Dutertre, Charles-Antoine; Khalilnezhad, Ahad; Reynoso, Glennys V; Coble, Vincent L; Lynn, Geoffrey M; Mulè, Matthew P; Martins, Andrew J; Finnigan, John P; Zhang, Xiao Meng; Hamerman, Jessica A; Bhardwaj, Nina; Tsang, John S; Hickman, Heather D; Ginhoux, Florent; Ishizuka, Andrew S; Seder, Robert A.

Nat Immunol ; 22(1): 41-52, 2021 01.

Artigo em Inglês | MEDLINE | ID: mdl-33139915

13.

Lack of affinity signature for germinal center cells that have initiated plasma cell differentiation.

Sutton, Henry J; Gao, Xin; Kelly, Hannah G; Parker, Brian J; Lofgren, Mariah; Dacon, Cherrelle; Chatterjee, Deepyan; Seder, Robert A; Tan, Joshua; Idris, Azza H; Neeman, Teresa; Cockburn, Ian A.

Immunity ; 57(2): 245-255.e5, 2024 Feb 13.

Artigo em Inglês | MEDLINE | ID: mdl-38228150

14.

Protein Interaction Mapping Identifies RBBP6 as a Negative Regulator of Ebola Virus Replication.

Batra, Jyoti; Hultquist, Judd F; Liu, Dandan; Shtanko, Olena; Von Dollen, John; Satkamp, Laura; Jang, Gwendolyn M; Luthra, Priya; Schwarz, Toni M; Small, Gabriel I; Arnett, Eusondia; Anantpadma, Manu; Reyes, Ann; Leung, Daisy W; Kaake, Robyn; Haas, Paige; Schmidt, Carson B; Schlesinger, Larry S; LaCount, Douglas J; Davey, Robert A; Amarasinghe, Gaya K; Basler, Christopher F; Krogan, Nevan J.

Cell ; 175(7): 1917-1930.e13, 2018 12 13.

Artigo em Inglês | MEDLINE | ID: mdl-30550789

15.

Interfaces of Malignant and Immunologic Clonal Dynamics in Ovarian Cancer.

Zhang, Allen W; McPherson, Andrew; Milne, Katy; Kroeger, David R; Hamilton, Phineas T; Miranda, Alex; Funnell, Tyler; Little, Nicole; de Souza, Camila P E; Laan, Sonya; LeDoux, Stacey; Cochrane, Dawn R; Lim, Jamie L P; Yang, Winnie; Roth, Andrew; Smith, Maia A; Ho, Julie; Tse, Kane; Zeng, Thomas; Shlafman, Inna; Mayo, Michael R; Moore, Richard; Failmezger, Henrik; Heindl, Andreas; Wang, Yi Kan; Bashashati, Ali; Grewal, Diljot S; Brown, Scott D; Lai, Daniel; Wan, Adrian N C; Nielsen, Cydney B; Huebner, Curtis; Tessier-Cloutier, Basile; Anglesio, Michael S; Bouchard-Côté, Alexandre; Yuan, Yinyin; Wasserman, Wyeth W; Gilks, C Blake; Karnezis, Anthony N; Aparicio, Samuel; McAlpine, Jessica N; Huntsman, David G; Holt, Robert A; Nelson, Brad H; Shah, Sohrab P.

Cell ; 173(7): 1755-1769.e22, 2018 06 14.

Artigo em Inglês | MEDLINE | ID: mdl-29754820

16.

Guidelines and definitions for research on epithelial-mesenchymal transition.

Yang, Jing; Antin, Parker; Berx, Geert; Blanpain, Cédric; Brabletz, Thomas; Bronner, Marianne; Campbell, Kyra; Cano, Amparo; Casanova, Jordi; Christofori, Gerhard; Dedhar, Shoukat; Derynck, Rik; Ford, Heide L; Fuxe, Jonas; García de Herreros, Antonio; Goodall, Gregory J; Hadjantonakis, Anna-Katerina; Huang, Ruby Y J; Kalcheim, Chaya; Kalluri, Raghu; Kang, Yibin; Khew-Goodall, Yeesim; Levine, Herbert; Liu, Jinsong; Longmore, Gregory D; Mani, Sendurai A; Massagué, Joan; Mayor, Roberto; McClay, David; Mostov, Keith E; Newgreen, Donald F; Nieto, M Angela; Puisieux, Alain; Runyan, Raymond; Savagner, Pierre; Stanger, Ben; Stemmler, Marc P; Takahashi, Yoshiko; Takeichi, Masatoshi; Theveneau, Eric; Thiery, Jean Paul; Thompson, Erik W; Weinberg, Robert A; Williams, Elizabeth D; Xing, Jianhua; Zhou, Binhua P; Sheng, Guojun.

Nat Rev Mol Cell Biol ; 21(6): 341-352, 2020 06.

Artigo em Inglês | MEDLINE | ID: mdl-32300252

17.

mTOR Signaling in Growth, Metabolism, and Disease.

Saxton, Robert A; Sabatini, David M.

Cell ; 168(6): 960-976, 2017 03 09.

Artigo em Inglês | MEDLINE | ID: mdl-28283069

18.

Emerging Biological Principles of Metastasis.

Lambert, Arthur W; Pattabiraman, Diwakar R; Weinberg, Robert A.

Cell ; 168(4): 670-691, 2017 02 09.

Artigo em Inglês | MEDLINE | ID: mdl-28187288

19.

Structure of the interleukin-5 receptor complex exemplifies the organizing principle of common beta cytokine signaling.

Caveney, Nathanael A; Rodriguez, Grayson E; Pollmann, Christoph; Meyer, Thomas; Borowska, Marta T; Wilson, Steven C; Wang, Nan; Xiang, Xinyu; Householder, Karsten D; Tao, Pingdong; Su, Leon L; Saxton, Robert A; Piehler, Jacob; Garcia, K Christopher.

Mol Cell ; 2024 Apr 05.

Artigo em Inglês | MEDLINE | ID: mdl-38614096

20.

Author Correction: 'Stealth' corporate innovation: an emerging threat for therapeutic drug development.

Mastellos, Dimitrios C; Blom, Anna M; Connolly, E Sander; Daha, Mohamed R; Geisbrecht, Brian V; Ghebrehiwet, Berhane; Gros, Piet; Hajishengallis, George; Holers, V Michael; Huber-Lang, Markus; Kinoshita, Taroh; Mollnes, Tom E; Montgomery, Robert A; Morgan, B Paul; Nilsson, Bo; Pio, Ruben; Ricklin, Daniel; Risitano, Antonio M; Taylor, Ronald P; Mantovani, Alberto; Ioannidis, John P A; Lambris, John D.

Nat Immunol ; 20(11): 1556, 2019 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-31605100

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